Ethyl Cellulose EC Powder Suppliers and Factory in China for Pharma Grade
Ethyl Cellulose (EC) is a high-performance cellulose derivative engineered for specialized industrial and pharmaceutical applications. Characterized by its insolubility in water and excellent solubility in various organic solvents, EC serves as a critical functional polymer. It is widely utilized as a professional binder for tablets and granules, significantly enhancing structural hardness while minimizing brittleness to ensure product integrity.
Our Ethyl Cellulose is available in various viscosity grades (TZN series) and substitution levels, providing unmatched versatility for film-forming and sustained-release applications. From creating protective moisture barriers to controlling drug diffusion rates, this metabolically inert and chemically stable powder meets rigorous quality standards, including compliance with the Chinese Pharmacopoeia, ensuring safety and consistency for global manufacturers.
Detailed Parameters
| Appearance | White to off-white granules or powder | Ethoxy Content (Wt%) | 45.5% - 49.5% or more (K/N/T Series) |
|---|---|---|---|
| Drying Weight Loss | ≤ 3.0% | Burning Residue | ≤ 0.4% |
| Heavy Metals | ≤ 10 ppm | Arsenic Content | ≤ 3 ppm |
| Softening Point | 135 - 155°C | Relative Density | 1.07 - 1.18 g/cm³ |
| Stability Range | pH 3 - 11 (Acid and Alkali resistant) | Pharmacopoeia Std | Complies with CP 2020 (Part 4) |
Key Advantages
Superior Stability
Excellent chemical resistance across pH 3-11 and long-term storage stability without deterioration.
Controlled Release
Acts as an ideal skeleton material for sustained-release pills and microcapsules to retard release.
High Adhesion
Forms firm, tough films with excellent adhesion, ideal for masking tastes and protecting sensitive drugs.
Thermoplasticity
Possesses great thermoplastic properties, facilitating efficient extrusion granulation processes.
Water Insolubility
Completely insoluble in water, providing a robust barrier against dampness and humidity.
Versatile Solubility
Easily dissolvable in ethanol, acetone, toluene, and other organic solvents for flexible formulation.
Product Gallery
Management Platforms
Grade Selection
Choose from TZN5 to TZN200 viscosity grades to match your specific formulation needs.
Process Control
Advanced alkalization and etherification control for uniform substituent distribution.
Quality Assurance
Strict compliance with medical-grade standards and pharmaceutical registration numbers.
Solvent Optimization
Expert guidance on toluene/ethanol mixtures to optimize viscosity and dissolution.
Packaging Safety
Secure cardboard drums with medical PE woven bags for maximum purity and stability.
Storage Management
Controlled storage below 32°C with a 3-year validity period for long-term supply.
Application Dosage Comparison
| Typical Grade | Reference Dosage | Primary Application |
|---|---|---|
| TZN7/10/20/50 | 3% - 20% | Sustained-Release Coating |
| TZN20/100 | 10% - 20% | Microcapsule Fabrication |
| TZN7/10/20 | 1% - 5% | Tablet Floating Layer |
| TZN10/20 | 2% - 6% | Granulation Binder |
| Customized | Variable | Specialized Film-forming |
Frequently Asked Questions
Q: What are the main applications of Ethyl Cellulose in pharmaceuticals?
It is primarily used as a binder for tablets to increase hardness, a film-forming agent for coating to mask taste and protect water-sensitive drugs, and as a skeleton material for sustained-release tablets and microcapsules.
Q: In which solvents is Ethyl Cellulose soluble?
EC is soluble in organic solvents such as ethanol, isopropanol, acetone, dichloromethane, and aromatic hydrocarbons like toluene. It is completely insoluble in water, glycerol, and propylene glycol.
Q: How does viscosity affect the properties of EC films?
Generally, as the viscosity of the Ethyl Cellulose grade increases, the toughness and tensile strength of the resulting film also increase, allowing for better diffusion control in coatings.
Q: Is Ethyl Cellulose safe for parenteral administration?
No. Ethyl Cellulose should not be used for parenteral medicine or intravenous injection solutions because it is not easily metabolized by the human body.
Q: What is the recommended storage condition for EC?
It should be stored in a dry environment below 32°C, away from open flames and materials with strong odors. The standard shelf life is 3 years.
Q: How to achieve the lowest viscosity when dissolving EC?
In a mixture of alcohol and aromatic hydrocarbons, the viscosity is at its lowest when the alcohol content is approximately 30-35%.
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