Ethylcellulose Aqueous Dispersion EAD Suppliers and Factory in China
Ethylcellulose Aqueous Dispersion (EAD) is a high-performance, nonionic cellulose ether designed to overcome the inherent hydrophobicity of standard ethylcellulose. By integrating specialized plasticizers and emulsifiers into a stable milky white suspension, EAD provides a water-based alternative for applications requiring exceptional water resistance, controlled drug release, and moisture-proof protective barriers.
Engineered for precision in the pharmaceutical and specialty chemical industries, TZ-EAD eliminates the need for hazardous organic solvents and additional plasticizers. It is an ideal solution for coating tablets, pellets, and granules, offering precise control over dissolution rates and ensuring superior stability across varying pH levels in the digestive tract.
Detailed Parameters
| Appearance | Milky white suspension | Total Solid Content (wt%) | 20-26% |
|---|---|---|---|
| pH Value | 4.0-7.0 | Viscosity (25℃, mpa.s) | ≤150 |
| Loss on Drying (wt%) | ≤71% | Heavy Metals (ppm) | ≤10 |
| Compliance Standard | Chinese Pharmacopoeia 2020 (Vol. 4) | Solubility | Water-insoluble (Dispersed) |
| Plasticizer | Pre-integrated | Odour | Ammonia-free |
Key Advantages
Moisture Protection
Low moisture permeability ensures excellent moisture-proof performance for sensitive preparations.
Controlled Release
pH-independent dissolution allows for precise time-controlled release regardless of the digestive location.
Optimized Handling
High solid content paired with low viscosity shortens coating time and prevents material sticking.
Precision Printing
Low viscosity ensures that engraved tablets maintain clear, sharp printing without blurring.
Eco-Friendly Safety
Water-based formula replaces organic solvents, eliminating flammable and explosive hazards.
Ready-to-Use
Pre-blended with plasticizers and ammonia-free, removing the need for additional additive steps.
Product Gallery
Management Platforms
Tablet Coating
Enhances appearance and protects solid dosage forms from humidity and oxygen.
Micropellet Control
Adjusts coating thickness to achieve specific therapeutic drug release patterns.
Skeleton Tablets
Used as a primary matrix material for the preparation of skeleton-type sustained-release tablets.
Solubility Tuning
Combination with HPMC allows for highly flexible adjustments of the drug release rate.
Packaging Options
Available in secure plastic containers of 3kg, 15kg, and 50kg to suit different scales.
Storage Protocol
Strict temperature control (5°C to 30°C) to maintain emulsion stability and quality.
Investment Return Comparison
| Feature | Organic Solvent Method | TZ-EAD Water-Based |
|---|---|---|
| Safety Risk | High (Flammable/Explosive) | Very Low (Safe) |
| Process Cost | High (Solvent Recovery) | Low (Water-Based) |
| Additive Effort | Manual Plasticizer Mixing | Pre-integrated |
| Environmental Impact | High VOC Emissions | Eco-friendly/Low VOC |
| Equipment Wear | Chemical Corrosion Risk | Standard Aqueous Processing |
Frequently Asked Questions
Q: What is the main advantage of using Ethylcellulose Aqueous Dispersion over standard EC?
Standard EC is hydrophobic and difficult to disperse in water. EAD provides a stable, ready-to-use aqueous suspension that eliminates organic solvents while retaining EC's water-resistant and controlled-release properties.
Q: How does TZ-EAD affect the drug release rate in tablets?
It acts as a hydrophobic barrier. By adjusting the concentration of the dispersion or mixing it with water-soluble polymers like HPMC, manufacturers can precisely tune the solubility and release speed of the active ingredient.
Q: Does TZ-EAD require the addition of separate plasticizers?
No, TZ-EAD is formulated with integrated plasticizers, simplifying the production process and ensuring a consistent film quality without the need for extra additives.
Q: Is the coating performance affected by pH changes in the gastrointestinal tract?
One of the primary strengths of EAD is that its dissolution characteristics are not affected by pH values, ensuring consistent drug delivery across different sections of the digestive system.
Q: What are the recommended storage conditions for these dispersions?
They should be stored in a cool, dry environment between 5°C and 30°C, protected from light and moisture, and kept tightly sealed to prevent contamination.
Q: Can TZ-EAD be used for both water-soluble and poorly soluble drugs?
Yes, TZ-EAD is versatile and suitable for a wide range of pharmaceutical agents, regardless of their inherent solubility, making it a universal choice for controlled-release coatings.
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