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However, the same insolubility poses challenges in other contexts, particularly when considering the digestibility of cellulose. Herbivores and certain microorganisms have developed specialized enzymes, such as cellulases, to break down cellulose into simpler sugars for energy. In contrast, humans and many other animals lack the ability to digest cellulose, which is why it is often referred to as dietary fiber. While fiber is essential for healthy digestion, its insoluble nature does not provide caloric energy, highlighting the dual nature of cellulose in nutrition.

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1. Water Solubility One of the most significant advantages of HPMC is its ability to dissolve in water, forming a clear and viscous solution. This property enables HPMC to act as a thickening agent, stabilizer, and emulsifier.