Hydroxypropyl Methylcellulose
Hydroxypropyl Methylcellulose (HPMC) stands out as a highly functional and adaptable material, serving as a cornerstone in numerous industrial applications. Its unique combination of properties, along with its ease of use and biocompatibility, makes it a preferred choice for formulators and manufacturers across diverse sectors.
┃ Appearance
HPMC usually exists in the form of white or off-white powder, which is odorless and tasteless, and miscible with water to form a transparent colloidal solution.
┃ Solubility
HPMC is highly soluble in water, forming clear, viscous solutions. The solubility of HPMC is influenced by the degree of substitution (DS) and the molar substitution (MS) of the hydroxypropyl and methyl groups. Generally, higher levels of substitution lead to increased solubility. HPMC is also soluble in some organic solvents, such as ethanol and methanol, but is insoluble in non-polar solvents like hexane and toluene.
┃ Viscosity
The viscosity of HPMC solutions is a critical property, which can be controlled by varying the molecular weight and degree of substitution. HPMC is used as a thickening agent in many applications, including pharmaceuticals, cosmetics, and food products. The viscosity of HPMC solutions increases with concentration and temperature, making it an excellent choice for formulations requiring specific rheological properties.
┃ Rheology Control
HPMC exhibits pseudoplastic behavior, meaning its viscosity decreases with increasing shear rate. This thixotropic property is beneficial in applications where the material needs to flow under stress but regain its viscosity when at rest. For example, in construction, HPMC is used in tile adhesives and grouts to improve workability and prevent sagging
┃ Thermal stability
HPMC exhibits good thermal stability, with a decomposition temperature typically above 200°C. This makes it suitable for use in high-temperature processes, such as hot-melt extrusion and film coating. However, prolonged exposure to high temperatures can lead to degradation, so it is important to control processing conditions to maintain the integrity of the polymer.
┃ Surface Activity and Emulsification
HPMC acts as a surface-active agent, reducing the surface tension of water and other liquids. This property makes it useful as an emulsifier and stabilizer in various formulations. HPMC can help to stabilize emulsions and suspensions, preventing phase separation and ensuring uniform distribution of components.
┃ Water Retention and Hydration Properties
HPMC has excellent water retention and hydration properties, which make it useful in construction materials, such as tile adhesives, grouts, and plaster. In these applications, HPMC helps to improve workability, extend open time, and enhance the overall performance of the material.
Types of HPMC
Based on Viscosity
┃ Low Viscosity HPMC
Viscosity Range: Typically below 100 mPa·s at 2% solution.
Applications: Low viscosity HPMC is used in applications where a thin, easily pourable solution is required. It is commonly used in pharmaceuticals as a binder and disintegrant, in cosmetics as a thickener and emulsifier, and in food products as a stabilizer and texture modifier.
┃ Medium Viscosity HPMC
Viscosity Range: Between 100 and 4,000 mPa·s at 2% solution.
Applications: Medium viscosity HPMC is used in applications that require a balance between flowability and thickening. It is widely used in the construction industry as a water retention agent in tile adhesives and grouts, and in the food industry as a thickener and stabilizer.
┃ High Viscosity HPMC
Viscosity Range: Above 4,000 mPa·s at 2% solution.
Applications: High viscosity HPMC is used in applications where a highly viscous solution is needed. It is commonly used in the construction industry as a thickener in dry-mix mortars and plasters, and in the pharmaceutical industry as a controlled-release excipient.
Specialized HPMC Variants
┃ Pharmaceutical Grade HPMC
Characteristics: These types meet strict regulatory standards for purity and consistency, making them suitable for use in pharmaceutical formulations.
Applications: Used in tablets, capsules, and other drug delivery systems.
┃ Food Grade HPMC
Characteristics: These types are approved for use in food products and meet food safety standards.
Applications: Used as thickeners, stabilizers, and emulsifiers in a variety of food products.
┃ Industrial Grade HPMC
Characteristics: These types are designed for industrial applications and may have a broader range of specifications.
Applications: Used in construction, paint, and other industrial processes.
Construction Industry
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│ Mortars and Plasters
│ Tile Adhesives and Grouts:
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│ Self-Leveling Compounds:
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│ Interior and Exterior Wall Putty:
Paints and Coatings Industry
│ Water-Based Paints
│ Textile Coatings
│ Drug Formulation
│ Oral and Topical Solutions
│ Thickening and Stabilizing
│ Emulsification and Foaming
│ Edible Films and Coatings
│ Skin Care Products
│ Hair Care Products
│ Toothpaste
│ Agriculture
│ Paper and Packaging
│ Environmental Applications
Technological advantage and innovation
│ Advanced production technology
To ensure the superior quality, stability, and consistency of our Hydroxypropyl Methylcellulose (HPMC) products, we employ advanced technologies throughout production. Utilizing precision automated systems for raw material selection and processing, we maintain strict control over particle size and distribution. Continuous monitoring with real-time analytics guarantees uniform viscosity and gelation properties. Our cleanroom facilities and stringent quality assurance protocols, including comprehensive testing at every stage, uphold the highest standards. Advanced packaging techniques further protect product integrity, ensuring reliable performance in diverse applications.
│ Research and development capability
At TangZhi, we lead in cellulose innovation with proprietary patents that enhance our products' performance and reliability. Our research drives advancements in fiber technology, ensuring superior quality. We hold key industry certifications and actively engage in strategic collaborations, elevating TangZhi’s technical expertise and professional standing. Our commitment to innovation sets TangZhi apart as a trusted leader in the cellulose field, delivering cutting-edge solutions that meet the highest standards of excellence.
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Through continuous R&D efforts, TangZhi has developed patented technologies in cellulose modification and application, significantly improving product functionality and sustainability. Partnering with leading institutions and industries, we ensure our innovations are at the forefront of the market, reinforcing TangZhi’s reputation for excellence and reliability in cellulose solutions.
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│ Environmental advantage
At TangZhi, we pride ourselves on our eco-friendly cellulose innovations, backed by prestigious ISO certifications. Our commitment to sustainability ensures that every product meets the highest environmental standards, appealing to environmentally conscious consumers. Discover the green advantage with TangZhi.
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FAQ
What are the main technical indicators of HPMC?
Most users are concerned about two indicators: hydroxypropyl content and viscosity. The higher the hydroxypropyl content, the better the water retention. The higher the viscosity, the better the water retention, relatively (not absolutely), and the higher the viscosity, the better it is to use in cement mortar.
How to simply and intuitively judge the quality of (HPMC)?
(1) Whiteness: Although whiteness cannot determine whether HPMC is good to use, and if whitening agents are added during the production process, it will affect its quality. However, most good products have good whiteness. (2) Fineness: The fineness of HPMC is generally 80 mesh and 100 mesh, and 120 mesh is less common. Most HPMC produced in Hebei is 80 mesh. The finer the fineness, the better it is generally. (3) Transparency: After HPMC is placed in water and forms a transparent colloid, its transmittance is observed. The greater the transmittance, the better, indicating that there are fewer insoluble substances in it. (4) Specific gravity: The greater the specific gravity, the heavier the better. The higher the specific gravity, the higher the water retention.
Does the powdering of putty powder have anything to do with HPMC?
The powdering of putty powder is mainly related to the quality of lime lime, not HPMC. Low calcium content of lime lime and improper ratio of C0 and Ca(0H)2 in lime lime will cause powdering. If there is some relationship with HPMC, then poor water retention of HPMC will also cause powdering.
Customer evaluation
We have received an overwhelming amount of positive feedback from our valued customers. Their testimonials consistently praise the superior quality and reliability of our products. We are confident that our commitment to excellence will continue to meet and exceed your expectations. Thank you for choosing us, and we look forward to serving you with the same high standard of quality.
Production Process
The manufacturing of HPMC begins with the purification of cellulose, typically obtained from wood pulp or cotton linters. The purified cellulose is then treated with an alkali, usually sodium hydroxide, to generate alkali cellulose. This is followed by the addition of methyl chloride and propylene oxide under controlled conditions, leading to the substitution of hydroxyl groups on the cellulose with methoxy and hydroxypropyl groups. The reaction conditions, such as temperature, pressure, and the molar ratio of reactants, are carefully managed to achieve the desired degree of substitution and molecular weight, which determine the final product's properties.
Precautions
┃ Storage
HPMC should be stored in a cool, dry environment to prevent moisture absorption, which can lead to clumping and degradation.
┃ Handling
Proper protective equipment, such as gloves and masks, should be worn during handling to avoid skin and eye irritation.
┃ Inhalation
Inhalation of fine HPMC powder should be avoided; ensure adequate ventilation in areas where it is handled.
┃ Disposal
Follow local regulations for the disposal of HPMC-containing waste, as it is generally considered non-hazardous but should not be released into the environment without proper treatment.
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