Hpmc 2910 Hypromellose 1
HPMC 2910 Hypromellose: Pharma-Grade Reliability Straight from the Factory
Sourcing consistent HPMC 2910 for tablet coatings or eye drops? We've shipped tons to US importers without a hitch. Factory-direct pricing, full specs, and samples on request.
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What Makes HPMC 2910 Stand Out Technically?
I've been in cellulose derivatives for over 15 years, handling everything from batch testing to container loading for US-bound shipments. HPMC 2910, or hypromellose as it's known in pharma circles, isn't just another powder. It's a specific hydroxypropyl methylcellulose grade tuned for medium viscosity—around 2,500-3,500 cps in 2% solution. That puts it right in the sweet spot for controlled-release coatings and suspension stabilizers.
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Production starts with refined cotton linter or wood pulp, etherified under alkaline conditions. We control the hydroxypropyl (about 7-12%) and methoxy (28-30%) substitution to hit USP/EP specs precisely. No shortcuts. Our lines run hot cellulose through pressurized reactors, then purify via dialysis to pull moisture below 5%.
One thing buyers overlook: gelation temp. HPMC 2910 gels at 58-64°C, perfect for hot-melt extrusion in tablets. But push it wrong, and you get clumping. We've tweaked drying curves to ensure free-flowing powder—bulk density 0.3-0.5 g/cm³.
| Property | HPMC 2910 Spec | Test Method |
|---|---|---|
| Appearance | White to off-white powder | Visual |
| Viscosity (2% in water) | 2500-3500 mPa·s | NDJ-1, 20°C |
| Loss on Drying | ≤5.0% | 105°C, 3h |
| pH (1% solution) | 5.0-8.0 | USP 61 |
| Heavy Metals | ≤10 ppm | USP <231> |
| Methoxy | 28.0-30.0% | USP |
| Hydroxypropyl | 7.0-12.0% | USP |
These aren't pulled from thin air. Every batch gets HPLC verification and microbial counts under USP <61>/<62>. We've rejected loads over 0.1% insoluble residue—common in lesser grades.
Short note on stability: Sealed drums keep it viable 24 months at 25°C. Heat over 40°C? Viscosity drops. Store smart.
Real-World Applications Where HPMC 2910 Delivers
Pharma formulators love it for aqueous film coatings—uniform, oxygen barrier without cracking. Dissolves clear, no turbidity. We've supplied for generics hitting 90%+ yield on extended-release metformin tabs.
- Tablet Binders: Wet granulation holds 2-5% for robust tablets. No over-disintegration.
- Eye Drops: Viscosity builds at 0.3-1%, tear film mimic. Sterile grades available.
- Capsule Shells: Veg alternatives to gelatin. Pin-seal on HPMC 2910 shells cuts leaks.
- Construction Mortars: Though pharma-focused, it thickens tile adhesives—water retention up to 130%.
- Food Thickening: E464 approved, stabilizes suspensions in sauces.
In one run, a Midwest US tableting op swapped to our HPMC 2910. Batch times dropped because less dust. Operational tweak, not magic.
Pro Tip: For high-shear mixers, pre-hydrate in 40% isopropyl alcohol. Speeds dispersion, cuts lumps.
How to Source HPMC 2910 Without Procurement Headaches
Procurement directors hit snags with inconsistent suppliers—viscosity swings kill formulations. Check factory audits first. We passed FDA-type inspections; papers available.
Lead times: 15-25 days FOB Tianjin. 20ft container holds 16-18MT, palletized 25kg bags. Incoterms? Flexible—DDP to US ports if volume justifies.
- Verify USP/EP/JP compliance docs.
- Test sample viscosity in your conditions.
- Ask for COA batch history—traceability matters.
- Factor MOQ: 1MT trials ok.
- Watch tariffs: HS 3912.39, US duties low.
Common pitfall: Cheap imports with high ash content fouls fillers. Ours <1%. Pay for purity.
Our Hebei plant: 140,000㎡, 40,000 tons/year capacity. Automated lines from Japan/Germany. Export to 50+ countries, REACH registered.
Frequently Asked Questions from Importers
Is HPMC 2910 the same as hypromellose K4M?
Close. K4M hits ~4000 cps; our 2910 is milder for lower viscosity needs. Both pharma-grade, interchangeable in many coatings.
What's your pricing per ton?
FOB $3,200-4,200/MT, volume tiers apply. Quote reflects purity, packing. Email for current sheet.
Can you do custom viscosity?
Yes, OEM from 5-200,000 cps. Min run 5MT.
Shipping to USA—any issues?
Weekly sailings via COSCO. Duty ~2.5%. Full docs for FDA entry.
Vegan and Halal certified?
Plant-based, Halal/Kosher on request.
Feedback from Procurement Teams
"Switched from Indian supplier—viscosity consistent now. Samples arrived fast, full container on time."
- Mike R., Purchasing Manager, Ohio Pharma Co.
"Used in eye drop base. No microbial flags on import testing. Good value vs. Dow."
- Sarah L., QC Director, Texas Lab.
"Tile adhesive trials worked well. Water retention held up in hot mixes. Repeat order coming."
- Carlos M., Ops Manager, Florida Contractor.
"OEM run for custom grade delivered as promised. Logistics smooth to LA port."
- Raj P., Supply Chain Lead, California Distributor.
Li Wei
Export Director at Tang Zhi Technology (Hebei) Co., Ltd.
15+ years in cellulose export, handled 500+ US shipments.
Ready to Source Your HPMC 2910?
No risk—free samples, detailed COA, engineer consult. We've got your back on compliance and delivery.
TANG ZHI TECHNOLOGY (HEBEI) CO., LTD
Room 2308, Dongsheng Plaza 2, No. 508 Zhongshan East Road, Chang’an District, Shijiazhuang, Hebei, China
Phone/Whatsapp: +86-15032625168
