Hpmc 2910 Hypromellose
HPMC 2910 Hypromellose: Reliable Pharma-Grade Excipient from Factory Direct
Sourcing consistent HPMC 2910 for tablets, capsules, or construction thickeners? We've shipped tons to US importers without batch variability issues.
+86-15032625168 | admin@tangzhicellulose.com
By Li Wei, Export Director at Tang Zhi Technology (Hebei) Co., Ltd. – Over 12 years coordinating cellulose ether exports to North America and Europe. We've handled everything from urgent pharma trials to bulk construction shipments.
Table of Contents
- • What is HPMC 2910 Hypromellose?
- • Technical Specs and Viscosity Breakdown
- • Key Applications in Pharma and Beyond
- • Why Choose 2910 Over Other Grades
- • Procurement Guide for Importers
- • Our Factory Capabilities
- • Logistics from Hebei to Your Door
- • Certifications and Compliance
- • Real Buyer Feedback
- • Frequently Asked Questions
What Exactly is HPMC 2910 Hypromellose?
Procurement teams often hit roadblocks finding HPMC 2910 hypromellose that meets exact specs without jumping through supplier hoops. It's not just another cellulose derivative—it's a specific substitution type engineered for low to medium viscosity needs.
HPMC, or hydroxypropyl methylcellulose (also called hypromellose), starts as purified cotton linter or wood pulp cellulose. We etherify it with methyl chloride and propylene oxide. The "2910" code breaks down like this: 29 means 28-30% methoxyl content, and 10 indicates 7-12% hydroxypropyl groups. This balance gives it solid film-forming properties with good solubility.
In our Jinzhou factory, we've dialed in production for pharma-grade consistency. Batches come out uniform because we use closed-loop alkaline processes and rigorous purification. No surprises on gel temperature—typically 58-64°C for 2910—or pH drift. Importers tell us this stability cuts their reformulation time.
Think about your last sourcing run. Did viscosity vary batch-to-batch? With HPMC 2910, it shouldn't. Our 2910 holds 3-20 mPa·s in standard 2% solutions, depending on the sub-grade. Perfect for eye drops where you need that silky flow, or dry mixes where clumping kills efficiency.
One operations manager from a Midwest pharma filler shared how switching suppliers mid-year wrecked their capsule fill weights. We've avoided that for dozens of US clients by sticking to EP/USP monographs. It's operational peace of mind.
Production-wise, we scale from lab trials (100kg) to full containers. Lead times hover at 7-14 days for stock grades. And pricing? Factory-direct keeps it competitive—often 20-30% below distributors when you buy pallet quantities.
Short note on sourcing pitfalls: Some exporters cut corners on hydroxypropyl content, leading to poor redispersibility. Test for that early. Our COA includes FTIR spectra proving the substitution ratios.
This grade shines in humid environments too. Water retention beats plain methylcellulose, critical for tile adhesives in coastal builds.
Technical Specs: HPMC 2910 in Detail
Diving into the numbers helps procurement specs match reality. Here's our standard HPMC 2910 profile, pulled from recent batches.
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | White to off-white powder | Visual |
| Methoxy (%) | 28.0 - 30.0 | USP <251> |
| Hydroxypropyl (%) | 7.0 - 12.0 | USP <251> |
| Viscosity (2% sol., 20°C) | 3 - 20 mPa·s | NDJ-1, 20 rpm |
| Loss on Drying | ≤5.0% | USP <731> |
| pH (1% sol.) | 5.0 - 8.0 | USP <791> |
| Heavy Metals | ≤10 ppm | USP <231> |
| Particle Size (100 mesh) | ≥98% | Sieving |
hpmc 2910/hypromellose hpmc hypromellose hypromellose hpmc
These aren't pulled from thin air. Every shipment includes a full COA. For custom viscosities, we tweak etherification dwell times—easy adjustment in our continuous reactors.
Viscosity matters most. Low-end 2910 (3cps) flows like water for sprays; higher (15-20cps) thickens gels without lumps. Contractors mixing gypsum plasters notice smoother application right away.
Applications: Where HPMC 2910 Delivers Real Value
US buyers use our 2910 across pharma, food, and construction. In tablets, it binds without swelling issues—holds up to 30% API loads. Capsule shells? Clear films with zero brittleness.
Eye drops and nasal sprays love the pseudoplastic flow. It shears thin on blinking, rebuilds viscosity off-shear. One formulator cut drip complaints by half after our batch.
- Pharma: Sustained-release matrices, coatings, suspensions.
- Construction: Tile adhesives (improves open time to 20-30 min), renders, self-leveling underlays.
- Food: Gluten-free thickener, ice cream stabilizer (E464 compliant).
- Cosmetics: Shampoos, lotions—non-irritating mucilage.
- Other: Paints for sag control, cleaners as anti-drip agents.
In tile work, it boosts adhesion on porcelain—pull-off strengths hit 1.2 N/mm² easy. We've seen masons finish jobs faster, less rework on vertical installs.
Pharma ops tip: Hydrate in hot water first for faster dispersion. Cuts mixing from 45 to 20 minutes.
Logistics note: Packs tight—25kg bags yield 20MT per 40HQ without waste.
HPMC 2910 vs. Other Grades: Quick Comparison
Why not K4M or E5? Depends on your need. 2910 sits in the sweet spot for solubility speed and moderate thickening.
| Grade | Viscosity (cps) | Solubility Temp | Best For |
|---|---|---|---|
| HPMC 2910 | 3-20 | Cold/Hot | Drops, adhesives |
| E5 (2906) | 5 | Cold | Coatings |
| K4M (2208) | 4000 | Hot | Sustained release |
| E15 (2910 high-vis) | 15 | Cold/Hot | Gels |
2910 wins on versatility. Faster hydration than higher methoxyl types, better moisture retention than HEC.
Procurement Guide: Smart Sourcing HPMC 2910
Purchasing directors know the drill—vet suppliers on more than price. Start with COA review: Insist on batch-specific heavy metals and microbial limits (<100 cfu/g total plate).
Common mistake: Ignoring particle size. Coarse powder dusts up in mixers; our 100-mesh pass rate keeps hoppers clean.

- Define dosage: 0.5-5% in pharma, 0.2-0.5% in mortars.
- Request samples with retention data—test your process.
- Negotiate MOQ: We drop to 1MT for trials.
- Factor freight: FOB Tianjin, 18-22 days to LA port.
- Lock pricing tiers: Better rates over 10MT.
Risk alert: Spot market volatility from cotton prices. Long-term contracts stabilize at $3.2-4.5/kg pharma grade.
Our Factory: Why Tang Zhi Stands Out
140,000 sqm site in Jinzhou, Hebei. 90,000 sqm buildings, automated lines churning 40,000 tons cellulose ethers yearly. HPMC 2910 runs on dedicated reactors—separate from MHEC or RDP to avoid cross-contam.
We've exported 5,000+ tons to USA since 2018. Clients like regional pharma packagers and drywall compounders. GMP cleanrooms for pharma grades, full effluent treatment.
Capacity lets us handle spikes—ramped 30% during 2022 shortages. No allocation games.
Quick fact: Our energy recovery cuts costs, passes savings to you.
Logistics and Shipping Realities
From Shijiazhuang hub to Tianjin port: 4-5 hours trucking. 20MT/40HQ standard, 25kg multiwall paper bags. Palletized for forklift handling.
US transit: 18-25 days West Coast. Duties? HS 3912.39—check your tariff schedule. We provide commercial invoices optimized for CBP.
Incoterms tip: CIF for small lots, FOB for regulars. Tracking via Maersk or COSCO apps.
Warehouse stock in NJ for rush—call to confirm.
Certifications: Full Compliance
- USP/EP
Pharma monograph - ISO 9001
Quality mgmt - Halal/Kosher
Food grade - REACH
EU compliant - RoHS
Restricted substances
Full certs on request. Audited yearly.
What Buyers Are Saying
"Switched to Tang Zhi's HPMC 2910 for our tile adhesive line. Open time improved noticeably, less callbacks from installers." – Mike R., Ops Mgr, Texas Contractor
"Pharma-grade consistency without premium pricing. Batches matched specs perfectly for our suspension trials." – Sarah L., Formulations Lead, NJ Lab
"Fast samples, quick scaling to 5MT order. Logistics smooth to Chicago." – Raj P., Procurement, Midwest Distributor
"Better water retention than previous supplier. Cut drying cracks in renders." – Carlos M., Plant Supervisor, FL
Frequently Asked Questions
Is your HPMC 2910 USP compliant?
Yes, fully meets USP-NF, EP, JP. Every batch tested.
What's the minimum order?
500kg for samples, 1MT standard. Flexible for OEM.
How long to USA?
18-25 days sea. Air for urgents.
Custom viscosity possible?
Yes, from 50 to 200,000 cps. 2-week lead.
OEM labeling?
Full support. Private label your brand.
Ready to Source HPMC 2910?
Eliminate supplier risks. Get consistent quality direct from factory.
Tang Zhi Technology (Hebei) Co., Ltd.
Room 2308, Dongsheng Plaza 2, No. 508 Zhongshan East Road, Chang’an District, Shijiazhuang, Hebei, China
Phone/Whatsapp: +86-15032625168 | Email: admin@tangzhicellulose.com
Contact Us | www.tangzhihpmc.com
Meta Title: HPMC 2910 Hypromellose Supplier | USP/EP Pharma Grade | Factory Direct Pricing
Meta Description: Reliable HPMC 2910 hypromellose for pharma excipients, tile adhesives, and more. USP/EP certified from Tang Zhi factory. Free samples, fast US shipping. Inquire now for specs and quotes.