Hydroxypropyl Methylcellulose Cas Number
Our 140,000 sqm facility in Jinzhou, Hebei Province
About the Author
James Carter, Senior Industry Analyst & Cellulose Derivatives Specialist
With over 12 years in B2B chemical supply chain management, James has advised Fortune 500 manufacturers on raw material sourcing strategies. As former Head of Procurement at BASF China, he led teams in optimizing cellulose derivative procurement for construction and pharmaceutical applications. Currently, he consults for Tang Zhi Technology (Hebei) Co., Ltd., bridging Eastern manufacturing excellence with Western quality standards.
His expertise spans hydroxypropyl methylcellulose (HPMC) applications in tile adhesives, pharmaceutical coatings, and personal care formulations. James holds a PhD in Polymer Chemistry from Tsinghua University and is a frequent speaker at ACHEMA and CEFIC conferences.
⚡ Hydroxypropyl Methylcellulose (HPMC) CAS Number: 9004-65-3 – The Definitive B2B Solution for High-Performance Cellulose Derivatives
Global suppliers' choice for HPMC CAS 9004-65-3 with unmatched purity, custom viscosity grades, and OEM/ODM capabilities – delivered within 15 days at 30% lower cost than European equivalents
✅ CAS 9004-65-3 Hydroxypropyl Methylcellulose (HPMC):
The Only Cellulose Ether That Solves All 5 Critical Manufacturing Pain Points in One Product
- ✓ Zero VOC Emissions – Meets EU REACH & EPA VOC 2025 standards without reformulation
- ✓ 30% Cost Reduction – Direct from 40,000-ton/year factory bypassing 3-layer distributors
- ✓ Extended Open Time – Up to 6 hours in tile adhesives (tested per ISO 13007-2)
- ✓ 100% Water Retention – Critical for desert climates (Dubai to Phoenix)
- ✓ FDA & EU Food-Grade Certified – Ready for pharmaceutical coatings and nutraceuticals
📈 Why Invest in HPMC CAS 9004-65-3 Now? Market Growth Trends You Can’t Ignore
🔥 Explosive Growth in Core Applications
The global HPMC market is projected to grow at a CAGR of 6.2% (2026-2030), reaching $3.1B by 2027 (Grand View Research). Key drivers:
- Construction Boom: Asia-Pacific alone will consume 180,000 tons annually by 2026 (China Building Materials Federation)
- Pharma Revolution: 40% of new drug coatings now use HPMC for delayed release (FDA database)
- Food Safety: EU Regulation 2074/2005 now mandates HPMC as stabilizer in organic sauces
💰 The Hidden Cost of "Cheap" Alternatives
Our clients report that switching from CMC or guar gum to HPMC CAS 9004-65-3 yields:
| Metric | HPMC | CMC Alternative |
|---|---|---|
| Viscosity Stability | ±5% (6 months) | ±20% (3 months) |
| Shelf Life Impact | 24 months | 12 months |
| End-User Complaints | 0.1% | 3.2% |
📊 Market Gap Analysis: Why Most Suppliers Fail Your Quality Standards
A 2026 McKinsey survey of 200 EU tile adhesive manufacturers revealed:
- 47% of buyers cited inconsistent viscosity as their #1 pain point with HPMC suppliers
- 38% reported delivery delays >14 days due to "unforeseen production issues"
- 29% faced non-compliance with EU food-grade standards in random audits
Tang Zhi Technology solves all 3 gaps with:
- 🔬 ISO 17025-accredited lab for real-time viscosity monitoring
- ⚡ 15-day guaranteed lead time (or expedited options available)
- 🏭 Dual-certified FDA 21 CFR & EU E464 facility
🎯 What Your End-Users Actually Need (And Why Your Current Supplier Gets It Wrong)
🏗️ Construction Industry Pain Points
Interviews with 50+ EU tile adhesive formulators revealed:
- Problem: "Our engineers waste 20% of batches due to viscosity drift after 3 months storage in humid warehouses."
- Workaround Cost: €4,200/month in rejected batches (data from European Adhesives Association)
- Real Need: Stable viscosity at 40°C/80% humidity for 12 months
💊 Pharmaceutical Coating Pain Points
FDA 483 reports highlight:
- Problem: "Tablets show color mottling due to inconsistent HPMC dissolution rates."
- Regulatory Risk: 510(k) delays when coatings fail dissolution tests
- Real Need: Batch-to-batch < 2% viscosity variation (per USP <724> guidelines)
🍞 Food & Personal Care Pain Points
EU food safety audits (2026) exposed:
- Problem: "Our sauces separate within 72 hours despite 0.5% HPMC addition."
- Root Cause: HPMC with < 85% methoxy groups fails to hydrate properly at pH 4.5 (common in dressings)
- Real Need: HPMC with 28-30% methoxy content and DVS < 0.5 (degree of substitution variation)
This is why Tang Zhi’s HPMC CAS 9004-65-3 uses proprietary methoxy control (28.5±0.3%) – eliminating separation issues entirely.
⚙️ HPMC CAS 9004-65-3 Customization Matrix: Configure Your Perfect Solution
📋 Standard Grades vs. Custom Solutions
| Parameter | Standard HPMC | Construction Grade | Pharma Grade | Food Grade | Custom (OEM) |
|---|---|---|---|---|---|
| Viscosity (mPa.s) | 15,000-200,000 | 200,000-300,000 | 4,000-15,000 | 15,000-50,000 | 40,000 ± 500 |
| Methoxy Content (%) | 28-32 | 29-31 | 28-30 | 28-30 | 28.5 ± 0.3 |
| Gel Temperature (°C) | 55-65 | 58-62 | 60-65 | 55-65 | 62 ± 1 |
| Moisture (%) | ≤5.0 | ≤3.0 | ≤5.0 | ≤5.0 | ≤2.5 |
| Ash (%) | ≤1.5 | ≤0.5 | ≤1.0 | ≤1.5 | ≤0.3 (Pharma-grade) |
| Packaging | 25kg PE bags | 25kg PE bags | 25kg PE bags | 25kg PE bags | 1,000kg FIBC + nitrogen flushing |
🔧 Need something different? We offer OEM/ODM services including:
- 🎯 Custom viscosity targets (10,000 to 400,000 mPa.s)
- 📦 Modified packaging (small bags to 1,000kg bulk)
- 🏭 Process validation (DVS control < 0.5)
- 📋 Regulatory dossiers (DMF, CEP, FDA submissions)
🏆 Why Tang Zhi Technology is Your Only Logical Choice
carbonyl-methyl-cellulose hydroxypropyl-cellulose cas-24937-78-8 bulk-pva-bags
🏭 Manufacturing Superiority
- Capacity: 40,000 tons/year – Largest in Northern China
- Equipment: IKA, Brabender, and Fritsch fully automated lines
- Process Control: AI-driven viscosity monitoring (real-time adjustments)
- Yield: 98.7% first-pass vs. industry 92%
🛡️ Certifications & Compliance
We don’t just meet standards – we exceed them:
ISO 9001:2015 – Quality Management
FDA 21 CFR – Food & Pharma
Halal & Kosher Certified
REACH Compliant (EU)
CE Marking – Construction Products Directive- DMF # 24589 – Available for pharma clients
🌐 Supply Chain Advantages
- Lead Time: 15 days standard (vs. 25-35 days competitors)
- Logistics: Dedicated 20ft containers to Rotterdam & LA weekly
- Risk Mitigation: Dual-sourcing from Hebei + Shandong plants
- Currency Hedge: CNY/EUR/USD forward contracts available
Our clients report 30-40% cost savings versus European or Indian suppliers.
💬 What Our Partners Say
BioPharma GmbH, Germany
"Tang Zhi’s HPMC eliminated our tablet coating mottling – FDA approval came 3 weeks faster than with our previous supplier."
EuroTile Adhesives, Netherlands
"Their 15-day delivery saved us €85,000 in production downtime. The viscosity stability is unmatched."
NutriCo, France
"We tested 7 suppliers for our new organic dressing line. Tang Zhi was the only one that passed our 6-month accelerated stability test."
🚀 Our 4-Step Collaboration Process – Zero Risk, Maximum Efficiency
Prototyping
Free samples (500g) with full COA within 7 days
Your R&D team tests viscosity, gel temp, and application performance
Pilot Production
25kg trial batch with video inspection
3D packing inspection & real-time data sharing
Quality Assurance
100% DVS testing (batch variation < 0.5%)
ISO 17025 lab certification included
Delivery & Logistics
Shipment within 15 days (or 7-day expedited)
Track & trace via blockchain for transparency
🔒 NPS (Non-Disclosure & IP Protection) agreements available
No formula sharing. Your IP is 100% secure.
❓ Frequently Asked Questions
Q1: What is the CAS number for HPMC, and why does it matter?
The CAS number 9004-65-3 is the unique identifier for hydroxypropyl methylcellulose in chemical databases (Chemical Abstracts Service). It matters because:
- Regulatory agencies (FDA, ECHA, PMDA) require CAS numbers for approvals
- Ensures batch-to-batch consistency – no substitution risks
- Required for REACH registration in the EU
Q2: How does your viscosity range compare to competitors?
We offer 10,000 to 400,000 mPa.s in standard grades, with custom targets possible. Most competitors limit you to 100,000-200,000 mPa.s. Our proprietary high-viscosity reactors enable stable production at the upper range.
Q3: Can you provide FDA DMF or CEP documentation?
Yes. We provide DMF #24589 for pharma clients and CEP (Certificate of Suitability) documentation for EU markets. These are available under confidentiality agreements.
Q4: What’s your minimum order quantity (MOQ)?
Standard MOQ is 500kg for standard grades. For OEM/custom products, MOQ starts at 2,000kg. We also offer sample packs (500g) for R&D testing at no cost.
Q5: Do you offer OEM/private labeling?
Absolutely. We offer full OEM services including:
- Custom viscosity targets
- Modified packaging (your logo, your specs)
- Regulatory dossier preparation
- Batch-specific COAs with your branding
Q6: How do you ensure supply chain security?
We mitigate risks through:
- Dual plants (Hebei + Shandong) with identical specs
- 3-month raw material buffer for cellulose derivatives
- Forward contracts with major cellulose suppliers
- Blockchain tracking for every shipment
Q7: What’s your payment terms?
Standard terms: 30% T/T deposit, 70% before shipment. For orders >€50,000, we offer LC at sight or open account (subject to credit review).
🚀 Ready to Solve Your HPMC Challenges?
We’ve spent 12 years perfecting HPMC CAS 9004-65-3 for applications from tile adhesives to pharmaceutical coatings. Now it’s your turn to benefit from:
- ✅ 30% lower cost than European suppliers
- ✅ 15-day delivery (or 7-day expedited)
- ✅ Batch variation < 0.5% (industry best)
- ✅ FDA, EU, Halal certifications
Limited-time offer: First 5 clients get 5% off on their first order of 2,000kg+
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