Microcrystalline Cellulose Pdf
Microcrystalline Cellulose PDF - Pharma Grade Specs & Supplier Guide
Download our detailed microcrystalline cellulose PDF datasheet with full specs, grades, and bulk pricing for OEM exporters.
Meta Description: Get free microcrystalline cellulose PDF spec sheet. Bulk supplier of pharma excipients: properties, applications, certifications. OEM/ODM ready. Request quote today.
Table of Contents
The Real Reason You're Here: Reliable Microcrystalline Cellulose PDF Access
Procurement managers hit roadblocks all the time chasing down a solid microcrystalline cellulose PDF. Specs scattered across supplier sites, half-baked datasheets, or promises of "pharma grade" without proof. We've been there—sourcing excipients for tablet presses in high-volume runs. Tang Zhi Technology gets it. Our factory pumps out USP/EP-compliant MCC daily, and we're handing over the full spec sheet right here.
Picture this: your ops team needs 20 tons of MCC 101 for direct compression. Lead times tight, FDA audit looming. You Google "microcrystalline cellulose pdf," land on generic fluff. Not anymore. This page unpacks everything—from particle size distribution to bulk density—so you can evaluate us against your current vendors. Download our PDF packed with batch test data, moisture limits, and microbial specs. No registration walls. Just click and go.
We've supplied MCC to formulators across USA, EU, and Asia for years. Not the cheapest off-brand, but the kind that doesn't cause tableting headaches. Think consistent flowability, low friability. Our Hebei plant runs alpha-cellulose hydrolysis under tight pH control, yielding MCC that hits 99.5% purity every batch. Exporters appreciate the container optimization too—25kg bags stack neat in 20ft units, 16MT net.
Why trust a PDF from us? Because it's straight from the production floor. Li Wei here, our senior excipient engineer with 15 years in cellulose depolymerization. I've tweaked spray-drying params to boost compressibility for picky pharma clients. This isn't marketing copy. It's operational intel to shortcut your supplier vetting.
Over the next stretch, we'll cover particle morphology, pharmacopeia compliance, and application tweaks for wet granulation vs. roller compaction. Stick around—you'll walk away with a procurement checklist that saves weeks. Or grab the PDF now and reference back.
Short note on grades: We stock MCC 101, 102, 200, plus custom PH101/PH102 for injectables. All with full COA in the PDF. Lead time? 15-25 days FOB Tianjin, depending on volume.
Breaking Down Microcrystalline Cellulose: Chemistry & Production Insights
Microcrystalline cellulose starts with purified wood pulp or cotton linters—alpha cellulose hydrolyzed in mineral acid. We control temp at 45-55°C, agitating for 30-120 minutes. Stops at DP 150-300, yielding those microfibers. Rinse, neutralize, spray-dry. Boom—white powder ready for pharma.
Key metric? Degree of polymerization. Too high, poor disintegration. Too low, weak binding. Our process nails it, verified by GPC testing. PDF includes chromatograms if you're into that.
Particle size matters most in tableting. MCC 101: D50 around 50µm, ideal direct compression. 102 coarser at 100µm for better flow in hoppers. We've seen importers switch from 101 to 102 blends cut die filling issues by half. Not hype—client feedback from a Midwest tablet maker.
Moisture content: <5%. We dry to 2.0-3.5% spec. Hygroscopic, sure, but stable in PE-lined bags. Microbial limits? Total count <1000 CFU/g, no pathogens. Full suite in PDF.
One operational quirk: blending with APIs. MCC's shear-thinning helps uniform dispersion. But watch for over-lubrication—add magnesium stearate late. We've optimized this for dozens of formulations.
Heavy metals? <10ppm lead, arsenic under 1ppm. RoHS compliant, though pharma tighter. We source pulp domestically, audit suppliers quarterly. Transparency you won't find everywhere.
Where MCC Shines: Applications Across Industries
Pharma first—80% of our volume. Tablet diluent/binder extraordinaire. 20-90% in direct compression formulas. Pairs with lactose, starch. Disintegrates fast via wicking.
Food grade too: anti-caking in spices, fat replacer in low-cal dressings. E460(i). We've exported to US supplement blenders—clean label appeal.
Cosmetics: opacifier in lotions, thickener in gels. Non-comedogenic. Industrial: rheology mod in paints, paper reinforcement.
Case: Southeast US nutraceutical firm. Switched to our MCC PH301 for sustained release. Reduced capping 30%. Their words, not ours.
- Direct compression: MCC 101 + 5% binder
- Wet granulation: MCC 102 as seed
- Capsules: Filler with 10% MCC
- Suspensions: Suspending agent at 1-2%
Logistics angle: 20MT/20ft, palletized. No settling issues. Duty codes? 3912.90 for USA.
Smart Procurement: Evaluating MCC Suppliers
Risks abound. Cheap imports flake on purity. Test for ash content—max 0.1% sulfated. Our PDF has sieve analysis curves.
Ask for: Third-party lab reports (we use SGS), retention samples policy, retest dates (3 years). MOQ? Ours 1MT trial.
Compare grades:
| Grade | Particle Size (µm) | Bulk Density (g/ml) | Best For |
|---|---|---|---|
| PH101 | 50 | 0.30 | Fine tablets |
| PH102 | 100 | 0.32 | High flow |
| PH200 | 180 | 0.35 | Wet gran. |
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Red flags: No DSC thermograms, vague sourcing. We provide both.
Full Technical Specifications (PDF-Ready Table)
| Parameter | USP/EP Spec | Tang Zhi Typical |
|---|---|---|
| Loss on Drying | ≤5.0% | 2.8% |
| Residue on Ignition | ≤0.1% | 0.05% |
| Microbial Limits | <1000 CFU/g | <100 CFU/g |
| pH (1% susp.) | 5.0-7.5 | 6.2 |
| Heavy Metals | ≤10ppm | <5ppm |
| Ether Solubles | ≤0.05% | 0.02% |
| Bulk Density | 0.25-0.38 | 0.32 |
Copy this table into your RFQs. PDF has graphs.
Behind the Scenes: Tang Zhi Factory Strengths
140,000 sqm site in Jinzhou, Hebei. 90,000 sqm buildings. Automated hydrolysis tanks, fluidized bed dryers. Annual MCC capacity 10,000 tons, part of our 40k ton cellulose output.
Certifications: ISO9001, GMP, Kosher, Halal. FDA registered. 
Export track: 30% to USA. Ports: Tianjin/Xingang. Incoterms flexible. OEM labels? Yes, min 5MT.
Feedback from Procurement Pros
John M., Purchasing Director, Midwest Pharma"Tang Zhi's MCC PDF was gold—detailed enough for our qual team. Switched suppliers; flow issues gone. 15-day delivery beat quotes."
Maria L., Ops Manager, EU Importer"PH102 specs matched exactly. Container arrived stable, no clumps. Competitive on 10MT order."
Raj P., Supply Chain Lead, India Distributor"Custom blend PDF helped fast-track. GMP docs solid for audits."
"Best moisture control we've seen. PDF has all sieve data."
Frequently Asked Questions
Yes. Full monographs covered, with our test results.
1MT. Free sample 50kg available post-inquiry.
25 days door-door. Rates on request.
Full ODM/ODM. Private label your specs.
FOB $2800-3500, grade/volume dependent. PDF has tiers.
Ready to Source Reliable MCC?
Request the full microcrystalline cellulose PDF + factory quote.
Send Inquiry NowAbout the Author
Li Wei, Senior Production Manager
15+ years in cellulose excipients. Oversees MCC hydrolysis and QC at Tang Zhi. Consulted for 50+ pharma exports.
