Hydroxypropyl Methyl Cellulose (HPMC) is a non-ionic, water-soluble cellulose ether widely used in construction, pharmaceuticals, and ophthalmology.

It plays a pivotal role in modifying the viscosity, water retention, and workability of formulations. Whether used in dry mix mortars or medical formulations, HPMC delivers consistent performance due to its unique physical and chemical properties.
In the construction industry, HPMC for mortar is a critical additive. It enhances water retention, improves workability, and increases open time, allowing workers to apply mortar more efficiently and with improved bonding strength. The compound also helps prevent cracking and segregation in the drying phase. Its compatibility with other cement-based additives makes it ideal for tile adhesives, renders, and masonry mortars.
Similarly, HPMC for putty powder improves the consistency and application performance of wall putty. It prevents sagging on vertical surfaces and enhances smoothness, ensuring better surface finish and durability. The addition of HPMC to putty powder formulations also extends the pot life and improves adhesion, making it a preferred additive for interior and exterior wall applications.
Beyond construction, HPMC also finds specialized applications in pharmaceuticals. One such example is flurbiprofen sodium with HPMC ophthalmic solution, a formulation designed for treating inflammation and pain in eye conditions. In this solution, HPMC acts as a viscosity-enhancing agent that increases ocular contact time, leading to better drug absorption and prolonged therapeutic effect.

HPMC is available in several grades, each suited to specific industrial needs. For example, HPMC K 100 M is a high-viscosity grade commonly used in extended-release pharmaceutical tablets. The HPMC K100M viscosity typically ranges from 80,000 to 120,000 mPa.s, making it suitable for matrix formulations requiring prolonged drug release. It also finds use in construction applications where strong water retention and thickening properties are required.
Another important grade is HPMC K15, a lower-viscosity variant often used in film coating and as a binder in tablet formulations. Its relatively low molecular weight makes it ideal for formulations that require quicker disintegration and dissolution.
Understanding the chemical structure of HPMC helps explain its functionality. It is a cellulose derivative in which some hydroxyl groups are replaced with methoxy and hydroxypropyl groups. This modification makes HPMC water-soluble, thermally gelling, and chemically stable. The ratio of methoxy to hydroxypropyl groups and the degree of substitution determine the viscosity and gelation temperature of the final product.
When sourcing HPMC, it’s important to consider quality, origin, and price. Leading producers like HPMC Solutions LLC offer high-grade cellulose ethers for pharmaceutical, food, and industrial use. Additionally, a reliable HPMC factory will have GMP-compliant facilities, standardized production lines, and robust quality control to ensure consistent batch performance.
Pricing is another important consideration. The HPMC powder price varies based on grade, viscosity, packaging, and origin. High-viscosity pharmaceutical grades such as HPMC K100M typically command higher prices than industrial or food-grade products. Bulk orders from established factories or distributors often come with price advantages, particularly for customers in the construction or pharmaceutical manufacturing sectors.

Hydroxypropyl Methyl Cellulose continues to prove itself as a versatile, efficient, and sustainable ingredient in numerous industrial and pharmaceutical applications. From enhancing the performance of mortars and putties in the construction industry to enabling advanced drug delivery systems and eye treatments, HPMC meets a wide array of functional demands.
The growing adoption of HPMC for mortar, HPMC for putty powder, and ophthalmic applications demonstrates the compound’s ability to adapt across industries. With major suppliers such as HPMC Solutions LLC and large-scale HPMC factory operations worldwide, the product is more accessible than ever.
As market demand increases and innovation continues in green building and drug delivery, the industry can expect greater investment in research to develop new HPMC grades, lower production costs, and improved solubility profiles. Understanding the chemical structure of HPMC, the characteristics of grades like HPMC K100M Ve HPMC K15, and the practical performance of ophthalmic solutions like flurbiprofen sodium with HPMC ophthalmic solution will be essential for manufacturers and formulators looking to stay ahead.
Answer:HPMC for mortar improves water retention, enhances workability, prevents segregation, and increases the bonding strength of the mix. It helps ensure consistent application and better performance on the job site.
Answer:HPMC for putty powder enhances smoothness, prevents sagging, and improves adhesion to wall surfaces. It also increases pot life and workability, allowing for better coverage and finish.
Answer:HPMC K100M is a high-viscosity grade used in sustained-release tablets and construction applications, whereas HPMC K15 has lower viscosity and is commonly used in tablet film coatings and binders. Their selection depends on the required viscosity and application purpose.
Answer:In flurbiprofen sodium with HPMC ophthalmic solution, HPMC acts as a thickener that increases the contact time of the drug with the eye, enhancing absorption and prolonging therapeutic action.
Answer:The HPMC powder price depends on grade, viscosity, and origin. Pharmaceutical grades like HPMC K100M cost more than industrial types. Trusted suppliers like HPMC Solutions LLC or a reputable HPMC factory can offer bulk discounts and reliable quality.